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Recent changes:
Oct 19 2009, 04:10 PM Added one risk variant for Europeans

Alzheimer's disease


These are the results of calculations comparing your genetic sequence to sequence of participants in studies published in the world literature on genetic risk for this disease.

How deCODEme calculates genetic risk

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Relevant risk variants from the literature


Population: Males of European ancestry
Locus Chromo-
some
Variant / SNP My Codes Relative
Risk
Genotype
frequency
Num. Cases / Num. Controls
APOE 19 rs429358
rs7412
TT
CC
0.58 60.7% 5107 / 6262
Farrer, LA et al. JAMA. 1997 Oct 22-29;278(16):1349-56.
CLU 8 rs11136000 CC 1.12 36.0% 5964 / 10188
Harold, D et al. Nat Genet. 2009 Oct;41(10):1088-93. Epub 2009 Sep 6.

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Chromosome location of relevant variants


The figure below shows the genomic location of the relevant variants, represented as stripes across the chromosome. Their color indicates your relative risk (red: high risk, yellow: medium risk, green: low risk). Hover over the variants with the mouse cursor to obtain more detailed information.

Alz

Keep in mind


These are the results of calculations comparing your genetic sequence to sequence of participants in studies published in the world literature on genetic risk for this disease. Read more about how deCODEme calculates risks.

This test was developed and its performance characteristics determined by the deCODE genetics Diagnostic Laboratory. It has not been cleared or approved by the U. S. Food and Drug Administration (FDA).

Change history


Date Change
Oct 19 2009, 04:10 PM Added one risk variant for Europeans